diff --git a/tests/integration/pipe-python-protobuf.sh b/tests/integration/pipe-python-protobuf.sh
new file mode 100755
index 000000000..b1e671051
--- /dev/null
+++ b/tests/integration/pipe-python-protobuf.sh
@@ -0,0 +1,90 @@
+#!/bin/bash
+#
+# Test protobuf serialization with Python client
+#
+# @author Steffen Vogel <stvogel@eonerc.rwth-aachen.de>
+# @copyright 2017, Institute for Automation of Complex Power Systems, EONERC
+# @license GNU General Public License (version 3)
+#
+# VILLASnode
+#
+# This program is free software: you can redistribute it and/or modify
+# it under the terms of the GNU General Public License as published by
+# the Free Software Foundation, either version 3 of the License, or
+# any later version.
+#
+# This program is distributed in the hope that it will be useful,
+# but WITHOUT ANY WARRANTY; without even the implied warranty of
+# MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
+# GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License
+# along with this program.  If not, see <http://www.gnu.org/licenses/>.
+##################################################################################
+
+SCRIPT=$(realpath $0)
+SCRIPTPATH=$(dirname ${SCRIPT})
+SRCDIR=$(realpath ${SCRIPTPATH}/../..)
+source ${SRCDIR}/tools/integration-tests-helper.sh
+
+CONFIG_FILE=$(mktemp)
+INPUT_FILE=$(mktemp)
+OUTPUT_FILE=$(mktemp)
+
+LAYER="unix"
+FORMAT="protobuf"
+
+NUM_SAMPLES=${NUM_SAMPLES:-20}
+NUM_VALUES=${NUM_VALUES:-5}
+
+# Generate test data
+villas-signal random -l ${NUM_SAMPLES} -v ${NUM_VALUES} -n > ${INPUT_FILE}
+
+case ${LAYER} in
+	unix)
+		LOCAL="/var/run/villas-node.server.sock"
+		REMOTE="/var/run/villas-node.client.sock"
+		;;
+
+	udp)
+		LOCAL="*:12000"
+		REMOTE="127.0.0.1:12001"
+		;;
+esac
+
+cat > ${CONFIG_FILE} << EOF
+{
+	"nodes" : {
+		"py-client" : {
+			"type" : "socket",
+			"layer": "${LAYER}",
+			"format" : "${FORMAT}",
+
+			"local" : "${LOCAL}",
+			"remote" : "${REMOTE}"
+		}
+	}
+}
+EOF
+
+# Start Python client in background
+python ${SRCDIR}/clients/python/villas.py unix &
+CPID=$!
+
+# Wait for client to be ready
+if [ "${LAYER}" = "unix" ]; then
+	while [ ! -S "${REMOTE}" ]; do sleep 0.1; done
+fi
+sleep 0.2
+
+villas-pipe -l ${NUM_SAMPLES} ${CONFIG_FILE} py-client > ${OUTPUT_FILE} < ${INPUT_FILE}
+
+kill ${CPID}
+
+# Compare data
+villas-test-cmp ${CMPFLAGS} ${INPUT_FILE} ${OUTPUT_FILE}
+RC=$?
+
+rm ${CONFIG_FILE} ${INPUT_FILE} ${OUTPUT_FILE}
+
+exit $RC